Poliovirus是小朋友的噩梦。这种病毒感染儿童后会侵染脊髓,造成下肢肌肉萎缩而导致失去行走能力。目前该疾病不能治愈,只能通过疫苗进行预防。Poliovirus对20世纪的美国肆虐多次,家长对这种疾病及其恐惧。Oshinsky的这本书通过描写poliovirus在美国的肆虐,围绕polio灭活疫苗的发明人Salk和减毒疫苗发明人Sabin的工作及其竞争,讲述了一段惊心动魄的历史。Sabin为首的病毒学家长期对Salk的蔑视,认为Salk只是一个技术员,在polio致病机理上没有什么贡献。Salk虽然拿了Lasker prize等著名奖项,但是始终被NAS拒于门外。

我最欣赏的是本文结束的一段话,这段话对书名Polio: An American Story进行了解释:

“In the strictest sense, these virtues were more generic than genetic, since Basil O’Connor was the son of Irish immigrants and Thomas Francis came from a Welsh steelworking family, while Jonas Salk, Albert Sabin, and Hilary Koprowski were the children of East European Jews. But all the more reason to view the conquest of polio as truly an Ameri- can story.”

 

 

 

 

 

 

Advertisements